Pubchem Assays currently used (Total Number: 1345)

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# Assay ID Assay Title Molecules Active
(Molecules Screened)
100 270 NCI In Vivo Anticancer Drug Screen. Data for tumor model Lewis Lung Carcinoma (subcutaneous) in B6D2F1 (BDF1) mice 105
(672)
101 292 NCI In Vivo Anticancer Drug Screen. Data for tumor model Sarcoma M5076 (intraperitoneal) in B6C3F1 mice 129
(583)
102 296 NCI In Vivo Anticancer Drug Screen. Data for tumor model Human Mammary Carcinoma MX-1 Xenograft (intrarenal inoculation) in NU/NU Swiss (nude) mice 144
(714)
103 328 NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in B6D2F1 (BDF1) mice 1574
(9217)
104 330 NCI In Vivo Anticancer Drug Screen. Data for tumor model P388 Leukemia (intraperitoneal) in CD2F1 (CDF1) mice 2467
(39943)
105 365 E. coli RNase H Inhibition 100
(105)
106 371 Human A549 Lung Tumor Cell Growth Inhibition Assay 278
(3039)
107 372 HIV-1 RNase H Inhibition 770
(99067)
108 374 In vitro Primary HTS Assay for MKP-1 100
(65023)
109 376 HERG Channel Activity 250
(1704)
110 377 MDR-1 353
(239)
111 422 HTS for 14-3-3 protein interaction modulators 314
(163541)
112 425 MKP-3 in vitro HTS assay 190
(114262)
113 429 HTS for Tumor Hsp90 Inhibitors 223
(63693)
114 430 Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7 cells) 1123
(61538)
115 431 Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7K cells) 1068
(61592)
116 436 HTS for BAP1 Enzyme inhibitors 346
(71189)
117 440 Primary HTS Assay for Formylpeptide Receptor (FPR) Ligands and Primary HTS Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands 181
(24099)
118 449 Primary HTS and Confirmation Assays for S1P1 Agonists and Agonism Potentiators 315
(55411)
119 460 Cathepsin L 100
(57721)
120 463 Cell Proliferation & 706
(55782)
121 464 Cell Proliferation & 331
(375)
122 465 Primary HTS assay for chemical inhibitors of antigen receptor-induced NF-kappaB activation 128
(61480)
123 466 Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Potentiator Assay 60K MLSMR 266
(242)
124 468 Dose Response Assays for S1P1 Agonists and Agonism Potentiators - Agonist Assay 60K MLSMR 281
(227)
125 485 Primary HTS Assay for S1P3 Antagonists 462
(168775)
126 521 HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target 727
(113651)
127 522 Primary Cell-based High Throughput Screening assay for activators of the nuclear receptor Steroidogenic Factor 1 (SF-1) 1225
(63699)
128 525 Primary Cell-based High Throughput Screening assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1) 359
(64565)
129 538 Complement factor C1s 102
(62034)
130 539 Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - PMK 319
(65097)
131 550 Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC Dose Response 136
(184)
132 555 Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK 316
(64949)
133 556 Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - DPM-DC 320
(65089)
134 560 Primary Cell-based High Throughput Screening assay for activators of the Retinoic Acid Receptor-related orphan receptor A (RORA) 979
(63945)
135 561 Primary Cell-based High Throughput Screening assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA) 278
(64646)
136 565 HIV-1 RT-RNase H MLSCN HTS MH077605 1250
(63988)
137 567 Primary HTS assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) agonists 366
(64558)
138 571 Primary Cell Based High Throughput Screening Assay for Antagonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) 641
(64283)
139 573 Primary Antimicrobial Assay for E. coli BW25113 & 1420
(63699)
140 574 Primary Cell Based High Throughput Screening Assay for Agonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E) 446
(64478)
141 575 Human Endothelial Cell Proliferation Assay 126
(9682)
142 576 Auto-fluorescence of compounds effecting screening of VLA-4 Integrin 146
(23610)
143 577 HTS to identify Inhibitors of West Nile Virus NS2bNS3 Proteinase 119
(65119)
144 578 Literature data for small-molecule inhibitors of EGF-R_Tyrosine _Kinase_Homo_sapiens 797
(163)
145 580 Human H69AR Lung Tumor Cell Growth Inhibition Assay 338
(9364)
146 589 qHTS Assay for Spectroscopic Profiling in 4-MU Spectral Region 6249
(47667)
147 590 qHTS Assay for Spectroscopic Profiling in A350 Spectral Region 6462
(43846)
148 593 qHTS Assay for Spectroscopic Profiling in Fluorescein Spectral Region 537
(39192)
149 598 Human H69AR Lung Tumor Cell Growth Inhibition Assay - 86K Screen 5141
(80068)
150 599 Counterscreen for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1): A cell-based dose-response assay for inhibition of the RAR-related orphan receptor A (RORA) 219
(138)
151 600 Dose-response cell-based assay for inhibitors of the nuclear receptor Steroidogenic Factor 1 (SF-1) 213
(146)
152 604 Primary biochemical high-throughput screening assay for inhibitors of Rho kinase 2 (Rhok2) 212
(59592)
153 612 Primary HTS assay for 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1a (5HT1a) antagonists 416
(61192)
154 618 Luminescent HTS for small molecule inhibitors of MT1-MMP transcription 537
(86212)
155 619 Fluorescence polarization assay for PLK1 inhibitors 518
(96590)
156 620 Fluorescent HTS Cytotoxicity/Cell viability assay (HT1080 cells) 364
(86393)
157 622 Voltage-Dependent Potassium Channel Beta Subunit (KvBeta) Negative Modulator Primary Screen 112
(12257)
158 626 Discovery of Novel Allosteric Modulators of the M1 Muscarinic Receptor: Agonist Primary Screen 1938
(61743)
159 628 Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Primary Screen 2180
(61481)
160 629 HTS of Estrogen Receptor- alpha Coactivator Binding inhibitors 1442
(84663)
161 630 HTS of Smad transcription factor inhibitors 251
(87809)
162 631 Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 1 (SRC-1) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) 811
(195444)
163 633 HTS for Estrogen Receptor-beta Coactivator Binding inhibitors 1114
(84991)
164 639 HTS of Estrogen Receptor- alpha Coactivator Binding Potentiators 1151
(84954)
165 640 LYP Inhibitors-an Autoimmunity Target - Primary screen 199
(96209)
166 641 Allosteric Modulators of D1 Receptors: Primary Screen 3414
(54294)
167 642 Allosteric Modulators of D1 Receptors: Confirmation Screen 1974
(265)
168 645 Isolation of Inhibitors of Her-Kinase Expression - 66K library screen 448
(64192)
169 647 Allosteric Modulators of D1 Receptors: Secondary Assay 2 1420
(820)
170 648 Human Endothelial Cell Proliferation Assay in 384-well format 925
(85244)
171 651 HIV-1 RT-RNase H MLSCN HTS MH077605 Confirmation Assay 390
(531)
172 677 Discovery of novel allosteric modulators of the M1 muscarinic receptor: Antagonist Confirmation Screen 723
(942)
173 680 Factor XIa Mixture HTS 120
(61985)
174 688 Yeast eIF2B assay 248
(26940)
175 693 High throughput fluorescence polarization-based assay to screen for small molecule inhibitors of the Polo box domain (PBD) of Plk1. 127
(96921)
176 696 Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase 1178
(94560)
177 697 LYP Activators-an Autoimmunity Target - Primary screen 103
(96305)
178 704 Primary biochemical high-throughput screening assay for inhibitors of the HIV Rev RRE RNA interaction (disruption of protein-RNA interaction) 769
(96119)
179 707 Novel sEH inhibitors for the therapeutic treatment of hypertension and inflammation 310
(90338)
180 709 Profiling the NIH Molecular Libraries Small Molecule Repository: Autofluorescence at 339/460 nm 3590
(61854)
181 710 Antimicrobial HTS Assay for E. coli BW25113 (wild type) - Expanded Screen 147
(97411)
182 713 Estrogen Receptor-alpha Coactivator Binding Inhibitors Dose Response Confirmation 221
(218)
183 719 Human Lung Fibroblast Proliferation Assay 937
(83952)
184 720 Primary biochemical high-throughput screening assay for antagonists of the interaction between the Eph receptor B4 (EphB4) and its ligand ephrin-B2 via TNYL-RAW peptide probe 143
(96745)
185 727 Primary biochemical high-throughput screening assay for inhibitors of Focal Adhesion Kinase (FAK) 811
(96077)
186 729 Primary Cell-Based High-Throughput Screening to Identify Agonists of the Sphingosine 1-phosphate receptor 2 (S1P2) 447
(96441)
187 731 Primary biochemical High Throughput Screening assay for agonists of the steroid receptor coactivator 3 (SRC-3) recruitment by the peroxisome proliferator-activated receptor gamma (PPARgamma) 519
(195736)
188 733 Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation 194
(196)
189 736 Primary Cell-Based High-Throughput Screening to Identify Antagonists of the Sphingosine 1-phosphate receptor 2 (S1P2) 207
(96681)
190 738 Screening for Modulators of Post-Golgi Transport, Control Strain 4851
(92676)
191 739 Modulators of Post-Golgi Transport 875
(96643)
192 746 Primary biochemical high-throughput screening assay for inhibitors of the c-Jun N-Terminal Kinase 3 (JNK3) 366
(59438)
193 748 High Throughput Fluorescence Polarization Screen for Bcl-B Phenotype Converters 102
(96313)
194 750 Luminescent HTS for small molecule activators of MT1-MMP transcription 142
(86337)
195 757 HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac wildtype 521
(189985)
196 758 HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab7 wildtype 107
(190389)
197 759 HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras wildtype 267
(190240)
198 760 HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype 365
(190143)
199 761 HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype 398
(190111)
200 764 HTS to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac activated mutant 219
(190281)

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