Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 242 15756

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=NNC)C#N 30.25 4.54e-14 14 243 30 15756
2 C(=NNC)(C#N)C 29.47 6.58e-10 10 243 22 15756
3 C(#N)C(=N)C 20.37 2.41e-09 11 243 35 15756
4 C(#N)C=N 20.26 8.10e-13 15 243 48 15756
5 O(N=CN)C(=O)C 5.93 0.00023 12 243 131 15756

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)N AND C(#N)C=N 41.26 1.04e-12 14 243 22 15756
2 c1(ccccc1)N AND C(=NNC)C#N 40.13 1.85e-11 13 243 21 15756
3 c1ccccc1 AND C(=NNC)C#N 37.82 2.83e-12 14 243 24 15756
4 c1(ccccc1)N AND C(#N)C(=N)C 34.12 1.56e-07 10 243 19 15756
5 c1ccccc1 AND C(=NNC)(C#N)C 30.87 3.73e-07 10 243 21 15756

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 CN AND C(#N)C=N AND c1(ccccc1)N 41.26 4.46e-10 14 243 22 15756
2 c1ccccc1 AND C(=NNC)C#N AND c1(ccccc1)N 40.13 7.90e-09 13 243 21 15756
3 c1ccccc1 AND C(=NN)C#N AND N(N)C 37.82 1.20e-09 14 243 24 15756
4 CN AND C(#N)C=N AND c1ccccc1 36.02 1.78e-10 15 243 27 15756
5 C(C)C AND c1(ccccc1)NN=C AND C(#N)C=N 36.02 4.21e-05 10 243 18 15756