Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 548 4619

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=CNC)(C(=O)C)C=C 19.19 2.42e-09 16 550 7 4619
2 C(=CNC)(C=CC)C=O 14.27 8.56e-09 17 550 10 4619
3 C(=CNC)(C=CC)CC 12.59 8.37e-09 18 550 12 4619
4 C(C(=O)C)Cl 8.39 5.40e-06 16 550 16 4619
5 C1(=O)C(=C)C=CC=C1 8.04 8.17e-09 23 550 24 4619

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=CCC)C=C AND C(=CNC)(C=CC)C=O 20.39 6.49e-07 17 550 7 4619
2 C(=O)(C)C AND C(=CNC)(C=CC)C=O 19.19 4.71e-06 16 550 7 4619
3 C(=CC=C)C=O AND C(=CNC)(C=CC)C=O 19.19 4.71e-06 16 550 7 4619
4 C(=C)NC AND C1(=O)C(=C)C=CC=C1 17.99 3.36e-05 15 550 7 4619
5 O=C AND C(=CNC)(C=CC)CC 16.79 9.00e-07 18 550 9 4619

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=CC)C AND C(=CNC)(C=O)C=C AND C(=CCC)C=C 20.39 0.00063 17 550 7 4619
2 C(=CC)C AND C(=CNC)(C=O)C=C AND C(=CC=C)C=O 19.19 0.0045 16 550 7 4619
3 O=C AND C(=CNC)(C=CC)CC AND C(=CNC)(C=CC)C=O 19.19 0.0045 16 550 7 4619
4 O=C AND C(=CNC)(C=CC)CC AND C(C=CC)C(=C)C 17.99 0.032 15 550 7 4619