Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 1036 126099

Table 1. Substructure Enrichment help

View Full Report

# Substructure Odds Ratio p-value kA Active kB InActive
1 c1cc(ccc1C=C)N 7.49 1.25e-14 31 1039 502 126099
2 C(=CC=C)C=C(C)C 5.35 5.58e-10 29 1039 657 126099
3 C(=CC=C)(C#N)C 5.21 4.48e-10 30 1039 698 126099
4 C(=CNCC)C=CC=C 4.46 1.90e-07 27 1039 734 126099
5 C(=C(CC)N)C=CC 4.34 1.71e-07 28 1039 783 126099

Table 2. Substructure Enrichment help

View Full Report

# Substructure Odds Ratio p-value kA Active kB InActive
1 C(#N)C=C AND C(=CC=C)C=C(C)C 16.64 2.72e-15 24 1039 175 126099
2 N(CC)(CC)C AND c1cc(ccc1C=C)N 14.86 3.33e-14 24 1039 196 126099
3 C(=CC=C)C=CC AND C(#N)C(=C)C 14.81 1.07e-15 26 1039 213 126099
4 N(CC)(C)C AND c1cc(ccc1C=C)N 13.66 3.93e-14 25 1039 222 126099
5 C(=CC=C)C=CC AND C(=CN(C)C)C=CC 13.19 8.86e-14 25 1039 230 126099

Table 3. Substructure Enrichment help

View Full Report

# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=CC=C)C=CC AND C(#N)C(=C)C AND C(=C)N 23.16 2.57e-16 25 1039 131 126099
2 C(=CC=C)C=CC AND C(#N)C(=C)C AND C(=CC)N 22.93 2.73e-15 24 1039 127 126099
3 C(#N)C=C AND C(=CC=C)C=C(C)C AND CN 17.23 1.47e-12 24 1039 169 126099
4 N(CC)(C)C AND c1cc(ccc1C=C)N AND c1(ccccc1)C=CC 16.18 5.93e-12 24 1039 180 126099
5 C(CC)CC AND C(=CC)(C#N)C AND C(N(C)C)CC 15.74 1.08e-11 24 1039 185 126099