Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 3121 287608

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1cc(ccc1NO)N 3.04 2.48e-13 75 3123 2272 287608
2 c1cc(ccc1N=O)N 3.01 6.28e-13 74 3123 2263 287608
3 N(C(CCC)C)CC(N)C 2.99 1.95e-12 72 3123 2213 287608
4 C(C(N(C)C)C)NC(C)C 2.73 5.34e-12 81 3123 2732 287608
5 C(NC(CC)C)C(NC)C 2.63 3.08e-11 81 3123 2826 287608

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)OCC AND c1(ccccc1)NC=N 3.97 1.01e-13 66 3123 1531 287608
2 N(CC=C)(CC)C AND N(C(CC)CC)C(=O)C 3.87 3.39e-13 66 3123 1569 287608
3 C(N(C)C)C=C AND N(C(CC)CC)C(=O)C 3.82 1.85e-13 68 3123 1637 287608
4 C(CCC)CC AND C(=NC)N(CC)C 3.6 6.83e-13 71 3123 1815 287608
5 C(N(CC)C)C=CC AND C(NCC)(CC)CC 3.57 9.92e-12 67 3123 1727 287608

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 Cl AND C(=N)N(C)C AND C(CO)NC 5.88 1.41e-19 66 3123 1033 287608
2 Cl AND C1(=CCC=CC1N)NC AND N(CC)(C)C 5.18 1.28e-16 66 3123 1173 287608
3 C(CCC)CC AND C(=NC)N(CC)C AND c1ccccc1 5.17 2.43e-17 68 3123 1209 287608
4 Cl AND N(C=N)(CC)C AND O(CC)C 5.02 3.01e-16 67 3123 1229 287608
5 Cl AND c1(ccccc1)OCC AND c1(ccccc1)CNC 4.95 5.00e-24 90 3123 1672 287608