Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 7905 5453

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(NC(C)(C)C)CC(C)N 43.39 3.81e-11 63 7916 1 5453
2 C(=CNCC)(Br)CC 42.7 6.46e-11 62 7916 1 5453
3 C(Br)CC(=C)C 42.02 1.09e-10 61 7916 1 5453
4 C(=CN)(Br)CC=CC 42.02 1.09e-10 61 7916 1 5453
5 C(=CNC)(Br)C(=O)CC 41.33 1.85e-10 60 7916 1 5453

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)N(C)C AND C(NC(C)C)C(O)C 68.19 3.27e-15 99 7916 1 5453
2 C1(=CCC=CC1C)N AND C(CN)(CN)O 66.81 9.43e-15 97 7916 1 5453
3 C1(=CCC=CC1C)N AND C(C(CN)O)NCC 65.44 1.35e-14 95 7916 0 5453
4 N(C)(C)C AND C(C(CNC)O)NC(C)C 63.37 1.32e-13 92 7916 1 5453
5 C(NCCCC)CCNC AND N(C(CCC)C)CCO 62.68 2.25e-13 91 7916 1 5453

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 N(CCC)C(C)C AND C(C(CNC)O)NCCC AND N(CCCC)CCO 60.61 8.59e-09 88 7916 1 5453
2 N(CCC)CCC AND C(C(CNC)O)NC(C)C AND N(CCCC)CCO 59.24 2.47e-08 86 7916 1 5453
3 N(CCC)CCC AND C(C(CNC)O)NC(C)C AND C(C(N)C)CC 58.55 4.19e-08 85 7916 1 5453
4 N(CCC)CCC AND C(C(CNC)O)NC(C)C AND N(CCCC)CCCC 57.17 1.20e-07 83 7916 1 5453
5 N(CCC)CCC AND C(C(CNC)O)NC(C)C AND N(CCC(N)C)CCCC 56.48 2.04e-07 82 7916 1 5453