Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 876 322700

Table 1. Substructure Enrichment help

View Full Report

# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=S)(NN=CC)N 4.44 1.27e-07 27 876 2237 322700
2 C(=C(C)C)(SC)CC 3.45 0.00025 23 876 2449 322700
3 C(=CCC)(S)CC 3.45 4.87e-05 26 876 2770 322700
4 C(=CSC)(CCCC)C 3.42 0.00018 24 876 2583 322700
5 C(=CCC)(SC)CC 3.34 0.00015 25 876 2750 322700

Table 2. Substructure Enrichment help

View Full Report

# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)C=NN AND C(=S)(N)N 7.85 4.96e-08 23 876 1079 322700
2 c1(ccccc1)C=NN AND C(=S)(NN=C)N 7.68 8.68e-07 21 876 1007 322700
3 c1(ccccc1)C=N AND C(=S)(N)N 6.94 6.91e-08 25 876 1326 322700
4 c1(ccccc1)C AND C(=S)(NN=CC)N 4.91 0.0015 22 876 1650 322700
5 c1(ccccc1)C=NN AND N(=CC)NCN 4.9 0.00013 25 876 1879 322700

Table 3. Substructure Enrichment help

View Full Report

# Substructure Odds Ratio p-value kA Active kB InActive
1 S=C AND c1(ccccc1)C=NN AND C(=S)(N)N 7.85 4.55e-05 23 876 1079 322700
2 c1(ccccc1)C=NN AND C(=S)(NN)N AND N(N=C)CN 7.68 0.00079 21 876 1007 322700
3 N(=CC)NC AND C(=S)(N)N AND c1(ccccc1)C=NN 7.57 0.00031 22 876 1070 322700
4 c1(ccccc1)C=N AND S=C AND C(=S)(N)N 6.94 6.33e-05 25 876 1326 322700
5 C(N)N AND c1(ccccc1)C=NN AND S 6.55 0.00066 24 876 1348 322700