Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 1315 323435

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C1(=CNC=NC1C)NC 122.88 1.49e-93 59 1316 118 323435
2 C1(=C(NC=NC1N)C)N 116.41 1.45e-84 54 1316 114 323435
3 C(=C(C=CO)C)C=CNC 112.04 4.26e-48 31 1316 68 323435
4 C(=CC=CN)(C=CO)C=C 97.09 5.92e-48 32 1316 81 323435
5 C(=C(C(=O)C)O)C=CC=C 79.7 2.81e-51 36 1316 111 323435

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C1(=CCN=CN1)NCC AND C1(=CNC=NC1C)NC 277.82 7.63e-93 52 1316 46 323435
2 C1(=CCC=CC1C)N AND C1(=C(NC=NC1N)C)N 260.22 1.72e-95 54 1316 51 323435
3 N(CC)CC AND C1(=C(NC=NC1N)C)N 227.33 7.43e-63 37 1316 40 323435
4 C1(=CCC=CC1C)N AND C1(=CNC=NC1C)NC 226.57 3.77e-102 59 1316 64 323435
5 C(#N)C(=C)C AND C(=CC=CNC)C=CC=O 138.52 5.44e-47 31 1316 55 323435

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 N(CC)CC AND C1(=CNC=NC1C)NC AND C1(=CCN=CN1)N(C)C 368.65 3.01e-57 33 1316 22 323435
2 C1(=CCC=CC1C)N AND C1(=C(NC=NC1N)C)N AND N(CC)CC 284.17 3.31e-62 37 1316 32 323435
3 C1(=CCN=CN1)NCC AND C1(=CNC=NC1C)NC AND c1(ccccc1)N 284 5.21e-90 52 1316 45 323435
4 C1(=CCC=CC1C)NC AND c1c(ncnc1C)N AND C1(=CNC=NC1C)NC 260.22 2.54e-92 54 1316 51 323435
5 C1(=CCC=CC1C)NC AND C1(=CNC=NC1)NC AND n1c(ccnc1)C 226.57 5.59e-99 59 1316 64 323435