Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 977 63929

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(c(ncnc1N)N)C 12.48 2.12e-22 34 978 178 63929
2 C(=O)(NCSC)C=CC=C 9.07 6.83e-19 35 978 252 63929
3 C(SC=CC)NC(=O)C=C 7.95 5.18e-13 27 978 222 63929
4 N(CSC=C)C(=O)C=CC 7.14 1.88e-11 26 978 238 63929
5 C(=NO)(C(=O)NC)C=CC 6.92 2.12e-23 52 978 491 63929

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)NN AND c1(c(ncnc1N)N)C 16.22 2.08e-22 34 978 137 63929
2 c1(ccccc1)NN=C AND C1(=CCN=CN1)NCC 15.53 4.79e-18 29 978 122 63929
3 C(N)C AND c1(c(ncnc1N)N)C 12.9 2.11e-17 31 978 157 63929
4 C(=N)C AND c1c(ncnc1N)N 12.43 1.09e-19 35 978 184 63929
5 c1(ccccc1)N AND c1c(ncnc1N)NC 12.1 2.46e-19 35 978 189 63929

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)NN AND c1(c(ncnc1N)N)C AND C(N)C 16.6 2.60e-17 31 978 122 63929
2 c1(ccccc1)NN AND c1c(ncnc1N)NN AND N=C 16.22 2.27e-19 34 978 137 63929
3 c1(ccccc1)NN AND C1(=CCN=CN1)NCC AND C(=N)C 15.53 5.21e-15 29 978 122 63929
4 c1(ccccc1)N AND c1c(ncnc1N)NC AND N=C 13.22 1.82e-17 35 978 173 63929
5 C(=N)C AND c1c(ncnc1N)N AND c1ccccc1 12.92 3.65e-17 35 978 177 63929