Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 423 352449

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 S(C(=S)N(C)C)C=CC=C 63.68 2.76e-26 19 424 248 352449
2 S(C=CC=C)C=S 54.89 1.02e-27 21 424 318 352449
3 S(C(=S)NCC)C=CC=C 53.87 2.67e-18 14 424 216 352449
4 C(=O)(N(C=S)C)C=CC=C 45.34 5.63e-26 21 424 385 352449
5 S(C=CC=CC)C=S 45.28 3.21e-17 14 424 257 352449

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C1(=C)SCNC1 AND c1(ccccc1)N=CC 675.38 3.73e-27 13 424 16 352449
2 S(C=S)C=CC AND c1(ccccc1)N=CC 623.43 1.54e-24 12 424 16 352449
3 S(C=S)C=CC AND c1(ccccc1)N=C 568.74 2.26e-26 13 424 19 352449
4 C1(=C)C(=O)NCS1 AND C1(=CCC=CC1N)N=C 302.27 2.96e-21 12 424 33 352449
5 C1(=C)C(=O)NCS1 AND C1(=CCC=CC1N)N 270.15 1.12e-22 13 424 40 352449

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C1C(=O)NCS1 AND c1(ccccc1)N=CC AND C(=CC)C 675.38 4.03e-24 13 424 16 352449
2 C(=S)(NCC=C)S AND c1(ccccc1)N=CC AND O 623.43 1.67e-21 12 424 16 352449
3 C(=N)(NC)C AND C1(=C)C(=O)NCS1 AND c1(ccccc1)NCC 623.43 1.67e-21 12 424 16 352449