Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 2579 325895

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(c(cccc1)Cl)Cl 3.34 4.01e-12 60 2581 2263 325895
2 C(OCCC)(CCN)CN 2.91 1.64e-13 81 2581 3507 325895
3 C(OCCC)(C(C)C)CN 2.9 1.40e-13 82 2581 3568 325895
4 C(OCCC)(C(CN)C)C 2.87 2.33e-13 82 2581 3601 325895
5 C(=CC)(O)N 2.83 1.42e-08 57 2581 2541 325895

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)Cl AND C(N(CCC)C)CC(O)C 8.35 3.29e-25 55 2581 831 325895
2 Cl AND C(N(CCC)C)CC(O)C 8.11 1.18e-25 57 2581 887 325895
3 c1(ccccc1)Cl AND N(CCO)(CCC)CCC 7.29 2.12e-22 55 2581 952 325895
4 Cl AND C(CNCC)(C(CN)C)O 7.13 2.36e-24 60 2581 1062 325895
5 C1(=CCC=CC1O)CC AND C(CNCC)(CCN)OC 7.1 3.85e-57 128 2581 2276 325895

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)CCN AND C(C(OC)C)N(CC)C AND c1(ccccc1)Cl 22.99 1.30e-43 55 2581 302 325895
2 Cl AND C(C(OC)CC)NCC AND c1(ccccc1)CC 20.91 1.77e-42 56 2581 338 325895
3 c1(ccccc1)CCN AND C(C(OC)C)NCC AND Cl 19.77 4.09e-42 57 2581 364 325895
4 c1(ccccc1)Cl AND C(C(OC)C)N(CC)C AND c1(ccccc1)CC 17.99 3.46e-39 56 2581 393 325895
5 Cl AND C(N(CC)C)C(CC)O AND c1(ccccc1)CC 17.58 7.34e-38 55 2581 395 325895