Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 1558 356286

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=CC=N)(CCC)N 7.77 2.76e-18 37 1560 1087 356286
2 C(=C(N)C)(CCC)C=N 7.11 1.59e-17 38 1560 1219 356286
3 C(CC(=CC)C)CCCC 6.36 1.03e-17 42 1560 1506 356286
4 C(=C(CC)N)C=N 6.04 1.85e-16 41 1560 1550 356286
5 C(=CC)(CCC)C=N 5.61 1.49e-14 39 1560 1586 356286

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(CCC)C=N AND C(=CCC)(NC)CC 14.34 6.59e-24 37 1560 589 356286
2 C(=CC)CO AND C(CCC)(CC)CC 12.68 1.16e-20 35 1560 630 356286
3 C(CCCC)NCC AND C(=CC=N)(CCC)N 12.54 1.66e-20 35 1560 637 356286
4 C(=CC)C=N AND N(CCC)(C(=C)C)C 12.52 1.75e-20 35 1560 638 356286
5 C(=CC=N)(NCC)C AND C(=CC=N)N(C)C 12.41 2.37e-20 35 1560 644 356286

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=CNC)C=N AND C(=CCC)(NC)CC AND C(CCCC)NCC 16.81 2.09e-22 36 1560 489 356286
2 N(C=C)(C)C AND C(=CC=N)(NCC)C AND C(CC)N 16.64 2.94e-22 36 1560 494 356286
3 N(C(=C)C)(CC)C AND C(=NC)(NC)C AND c1(ccccc1)OC 16.34 1.32e-23 38 1560 531 356286
4 C(CCC)C=N AND C(=CCC)(CC)N AND C(CCCC)NCC 16.34 8.45e-23 37 1560 517 356286
5 C(CCCC)NCC AND C(=CC=N)(CCC)N AND C(=CCC)(CC)N 15.82 9.93e-21 35 1560 505 356286