Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 1088 21094

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)C#CC 10.4 8.91e-19 35 1092 65 21094
2 C(=N)(SC)CNC 5.62 8.81e-18 51 1092 175 21094
3 c1cc(ccc1CF)C 5.18 6.01e-48 139 1092 518 21094
4 C1(=CC(C=CC1)C)Cl 4.86 1.02e-41 129 1092 512 21094
5 c1(c(cccc1)Cl)Cl 4.86 2.26e-41 128 1092 508 21094

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(F)F AND n1cc(ccc1OC)C 34.34 7.54e-25 32 1092 18 21094
2 c1(ccccc1)CF AND C(OCCCC)CNCN 31.6 1.10e-27 36 1092 22 21094
3 c1cc(ccc1N)C AND C(OCCC)(CN(C)C)C 30.43 3.11e-41 52 1092 33 21094
4 c1cc(ccc1N)C AND C(OC(CN)C)CCCC 29.94 1.07e-49 62 1092 40 21094
5 c1(ccccc1)CF AND C(CNC=O)(OCCC)C 28.97 1.91e-29 39 1092 26 21094

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(C(OC)CC)N(CC)C AND c1cc(ccc1CF)N AND C(N(CCC)C)CCOC 37.75 1.08e-32 43 1092 22 21094
2 C(C(OC)CC)N(CC)C AND c1cc(ccc1CF)N AND C(=O)CC 34.77 1.22e-33 45 1092 25 21094
3 c1(ccccc1)CF AND C(CNCC)(OCCC)C AND C(NC)NC 34.49 1.28e-15 25 1092 14 21094
4 C(F)F AND C1(=CCC=NC1O)C=O AND n1cc(ccc1OC)C 34.34 7.50e-22 32 1092 18 21094
5 C(C(OC)CC)N(CC)C AND c1cc(ccc1CF)N AND C(NCCC)C(CC)C 34.12 1.29e-40 53 1092 30 21094