Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 957 15031

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=CNN=C)C(=NC)C 6.06 7.50e-10 29 958 75 15031
2 C(=CNN)C(=NC)C 6.06 8.97e-12 34 958 88 15031
3 C(=CC(=N)C)(NN=CC)C 6.05 4.65e-09 27 958 70 15031
4 C(=CN(N)C)C(=N)C 6.01 2.14e-09 28 958 73 15031
5 C(=C(NN)C)C(=N)C 5.93 2.10e-10 31 958 82 15031

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(F)F AND N(C(=C)C)(N=C)C 7.68 3.35e-06 24 958 49 15031
2 C(=CN)CC AND C(CN)(F)F 7.68 3.35e-06 24 958 49 15031
3 C(=CN)CC AND C(CF)NC 7.67 9.75e-06 23 958 47 15031
4 C(=O)N AND C(=CC(=N)C)(NN=CC)C 7.38 6.77e-06 24 958 51 15031
5 C(=O)N AND n1(c(ccn1)N)CC 7.36 1.97e-05 23 958 49 15031

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(F)F AND N(C(=C)C)(N=C)C AND O 8.01 0.0027 24 958 47 15031
2 C(=CN)CC AND C(CN)(F)F AND O 7.84 0.0039 24 958 48 15031
3 N(N=C)(CC)C AND N(=C)CN AND F 7.84 0.011 23 958 46 15031
4 N(N=C)(CC)C AND N(=C)CN AND C(=O)N 7.69 0.00067 26 958 53 15031
5 C(=O)N AND C(=CC)(NN)N AND N(CC)(N)C 7.68 0.0056 24 958 49 15031