Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 3076 366862

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(COC=O)(NC=O)C 16.29 2.88e-51 66 3077 483 366862
2 C(=CC(=O)N)(N=CN)CN 14.34 5.68e-51 70 3077 582 366862
3 C(=C(C=O)N)(CNC)N=C 14.1 2.87e-51 71 3077 600 366862
4 C(=C(C=O)N)(C(=O)N)N=C 14.02 7.66e-52 72 3077 612 366862
5 C(=C(C=O)N)C(=O)NCC 13.75 2.65e-51 72 3077 624 366862

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=CC)NC AND C(COCC)(NCC)CC 34.3 1.25e-83 82 3077 285 366862
2 C(=CC)NC AND C(COCC)(NC=O)CC 32.62 4.94e-81 81 3077 296 366862
3 C(=CC)NC AND C(NC(=O)C)(COCC)C 28.22 1.33e-84 89 3077 376 366862
4 C(=CC)NC AND C(C(CC)N)OCC 27.21 1.95e-78 84 3077 368 366862
5 C(=CC)NC AND C(COCC)(NCC)C 26.49 1.91e-83 90 3077 405 366862

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=CC)NC AND C(COCC)(NCC)CC AND C(C)(C)C 45.62 1.15e-80 75 3077 196 366862
2 C(=CC)NC AND C(COCC)(NC=O)CC AND C(C)(C)C 45.01 3.98e-79 74 3077 196 366862
3 C(=CC)NC AND C(NC(=O)C)(COCC)C AND C(NC=O)(CCC)C 41.44 1.30e-66 65 3077 187 366862
4 C(=CC)NC AND C(COCC)(NCC)CC AND C(NC=O)CCC 40.15 7.45e-66 65 3077 193 366862
5 C(=CC)NC AND C(NC(=O)C)(COC)CC AND C(=O)(OCC)C 40.07 6.99e-84 81 3077 241 366862