Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 874 96635

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(NC(=O)C)OCC 8.58 2.79e-11 22 875 283 96635
2 C(NC=O)OCC 7.4 1.61e-10 23 875 343 96635
3 N(COC)C(=O)C 6.92 6.34e-10 23 875 367 96635
4 N(C(=O)C)CO 5.35 4.26e-08 24 875 495 96635
5 N(COC)C=O 5.06 1.29e-07 24 875 523 96635

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 N=C AND C(NC=O)OCC 14.86 5.62e-12 21 875 156 96635
2 NN AND C(NC(=O)C)OCC 13.97 1.86e-11 21 875 166 96635
3 c1(ccccc1)C=O AND C(NC(=O)C)OCC 12.53 1.51e-10 21 875 185 96635
4 N(C(C)C)(CC)C AND C1(=CCC=NC1)CC 11.2 1.31e-09 21 875 207 96635
5 C(=CC=CC)C=CN AND C(=C)(C=CC)OC 11.19 2.95e-10 22 875 217 96635

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)C=O AND O(CN)CC AND C(=N)C 21.67 4.13e-12 21 875 107 96635
2 N(C(C)C)(C)C AND C1(=CCC=NC1)CNC AND c1(ccccc1)N 19.65 2.71e-11 21 875 118 96635
3 c1(ccccc1)C=O AND C(OC)N AND C(=N)C 17.88 3.61e-12 23 875 142 96635
4 N=C AND C(NC=O)OCC AND c1ccccc1 16.92 4.83e-10 21 875 137 96635
5 NN AND C(OC)NC AND c1(ccccc1)C=O 15.77 1.88e-09 21 875 147 96635