Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 2066 4868

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(CCCCC)NC=CN 37.53 5.58e-13 32 2075 2 4868
2 N(CCCCC)C=[N](C)C 36.36 1.83e-12 31 2075 2 4868
3 C(CN(C=C)C)CCCC 21.11 6.26e-13 36 2075 4 4868
4 C(C(=C)CO)(CCO)C 18.76 5.96e-11 32 2075 4 4868
5 C(C(=CC)CO)(CCO)C 18.18 1.85e-10 31 2075 4 4868

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(CNC)CCC AND c1cc(ccc1Cl)C 72.72 4.37e-10 31 2075 1 4868
2 C(CCCC)OCC AND C(=CNC)(CC)C 68.03 5.00e-09 29 2075 1 4868
3 c1(ccccc1)CCN AND C(OCC)(CNC)C 68.03 5.00e-09 29 2075 1 4868
4 C(=C)(C=O)C AND C(COCC)CC=C 65.68 1.69e-08 28 2075 1 4868
5 C(=CC)(C=O)C AND C(COCC)CC=C 63.34 5.71e-08 27 2075 1 4868

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)CCC AND C(COCC)CCCO AND C(C)(C)C 84.45 1.38e-09 36 2075 0 4868
2 C(CCCC)OCC AND C(=CN)CC AND c1ccccc1 79.76 3.17e-08 34 2075 1 4868
3 C(CCCC)OCC AND C(=C)NC AND c1(ccccc1)CCC 79.76 3.17e-08 34 2075 1 4868
4 C(CCCC)OCC AND C(=CN)CC AND c1(ccccc1)CC 77.41 1.07e-07 33 2075 1 4868
5 C(CCCC)OCC AND C(=CN)(C)C AND c1(ccccc1)CCC 75.07 3.63e-07 32 2075 1 4868