Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 726 6915

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(CCCCC)CNC=C 49.12 7.54e-21 26 732 5 6915
2 C(CCCCC)CNC=N 35.08 2.20e-19 26 732 7 6915
3 C(CCCCC)NC=CN 28.34 7.10e-17 24 732 8 6915
4 N(CCCCC)C=[N](C)C 27.15 5.97e-16 23 732 8 6915
5 C(CN(C=C)C)CCCC 21.46 3.75e-16 25 732 11 6915

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=NC)NCC AND c1(c(cccc1)CC)Cl 99.19 1.86e-15 21 732 2 6915
2 N(CCC)C=N AND c1(c(cccc1)CC)Cl 85.02 1.99e-12 18 732 2 6915
3 C(CCC)CCC AND C(=CNC)N(C)C 75.57 2.08e-17 24 732 3 6915
4 C(CCC)CCC AND [N](=C)(C)C 72.42 2.07e-16 23 732 3 6915
5 N(CCC)C=N AND C1(=CCC=CC1C)Cl 62.97 2.00e-13 20 732 3 6915

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)Cl AND C(=NC=C)NCC AND C(C)C 170.04 9.61e-11 18 732 1 6915
2 C(=NC)NCC AND C1(=CCC=CC1C)Cl AND c1(ccccc1)CC 103.91 1.59e-13 22 732 2 6915
3 C(=NC)NC AND c1(c(cccc1)CC)Cl AND N(C=N)CC 99.19 1.63e-12 21 732 2 6915
4 C(CCC)CCC AND C(=NC)N AND F 94.46 1.68e-11 20 732 2 6915
5 N(CCC)C=N AND C1(=CCC=CC1C)Cl AND O 89.74 1.71e-10 19 732 2 6915