Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 2262 368843

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=NC)(N(CC)CC)N 8.32 3.57e-26 50 2264 978 368843
2 N(C(=N)NC)(CC)CC 7.44 4.81e-24 50 2264 1094 368843
3 N(C(=C)C)(CN)CC 7.2 2.23e-25 54 2264 1221 368843
4 N(C(=N)N)(CC)CC 6.92 1.44e-24 54 2264 1271 368843
5 N(C(=C)C)(C=N)CC 6.64 1.28e-36 82 2264 2011 368843

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(F)C AND N(C(=C)C)(C=N)C 23.07 7.54e-43 50 2264 353 368843
2 C(C)(F)(F)F AND N(C(=C)C)(C=N)C 23 7.43e-42 49 2264 347 368843
3 C(C)(F)F AND N(C=N)(C=C)CC 20.46 1.39e-39 49 2264 390 368843
4 C(C)(F)F AND N(C=CC)(C=N)C 17.11 1.49e-38 52 2264 495 368843
5 c1(ccccc1)CC AND N(C(=C)C)(C=N)CC 16.25 6.71e-36 50 2264 501 368843

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(C)(F)(F)F AND N(C(=C)C)(C=N)C AND C(=O)C 32.71 1.34e-45 49 2264 244 368843
2 C(F)C AND N(C(=C)C)(C=N)C AND O 28.78 3.72e-44 50 2264 283 368843
3 C(C)(F)F AND N(C=N)(C=C)CC AND O 25.58 7.37e-41 49 2264 312 368843
4 N(C(=C)C)(C=N)CC AND C(=NCC)N(CC)CC AND O(C)C 24.48 5.23e-40 49 2264 326 368843
5 C(F)F AND N(C(=C)C)C=N AND O(C)C 24.26 7.87e-40 49 2264 329 368843