Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 302 218414

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=NC=N)(NC(=O)C)SC 299.26 1.32e-24 12 302 29 218414
2 C(=NNC)OC(=O)C 198.88 8.86e-21 11 302 40 218414
3 N(=CNC=O)CC=CC=C 72.32 2.16e-17 12 302 120 218414
4 n1(nc(nc1)C)C(=O)C 60.65 7.96e-18 13 302 155 218414
5 N(C(=N)SC)(N=CC)C=O 60.65 7.96e-18 13 302 155 218414

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=O)(N(N)C)C AND C1(=CCC=CC1N)N=N 723.22 2.91e-25 12 302 12 218414
2 C(=NCC)(NC(=O)C)SC AND N(=CC=C)NC=O 602.68 4.66e-20 10 302 12 218414
3 C(=CC)C AND C(=NNC)OC(=O)C 441.97 4.53e-21 11 302 18 218414
4 CO AND N(CSC)(N=CN)C(=O)C 380.64 2.26e-18 10 302 19 218414
5 N(=C)C AND N(CSC)(N=CN)C(=O)C 299.26 2.01e-21 12 302 29 218414

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=O)(N(N)C)C AND C1(=CCC=CC1N)N=N AND c1(ccccc1)C 1084.83 6.91e-24 12 302 8 218414
2 C(=NCC)(NC(=O)C)SC AND N(=CC=C)N(C)C AND C(=O)NN 602.68 3.55e-17 10 302 12 218414
3 C(=CC)C AND C(=NNC)OC(=O)C AND c1ccccc1 556.32 6.79e-17 10 302 13 218414
4 c1(ccccc1)C=O AND c1(SC)[nH]ncn1 AND C(=O)NC 482.15 2.23e-16 10 302 15 218414
5 C(=CC)C AND C(=NN)(OC=O)C=C AND C(=O)C 441.97 3.44e-18 11 302 18 218414