Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 354 195627

Table 1. Substructure Enrichment help

View Full Report

# Substructure Odds Ratio p-value kA Active kB InActive
1 c1cc(ccc1NN)N 31.99 1.50e-18 17 356 292 195627
2 c1nc(ccc1C=C)C 30.43 2.90e-19 18 356 325 195627
3 c1(c(cccn1)C=C)S 24.39 1.55e-18 19 356 428 195627
4 c1cc(ccc1C=C)N 22.72 1.47e-31 33 356 798 195627
5 c1(cc(ccc1C)N)O 21.84 6.06e-12 13 356 327 195627

Table 2. Substructure Enrichment help

View Full Report

# Substructure Odds Ratio p-value kA Active kB InActive
1 c1cc(ccc1C=C)N AND c1c(cccc1N)O 73.26 3.39e-17 14 356 105 195627
2 c1cc(ccc1C=C)N AND c1(cc(ccc1C)N)O 72.89 9.99e-16 13 356 98 195627
3 c1cc(ccc1C=C)N AND c1c(cccc1O)NC 70.15 4.35e-14 12 356 94 195627
4 c1cc(ccc1C=C)N AND c1c(cccc1N)OC 68.03 2.45e-15 13 356 105 195627
5 c1(ccccc1)OCC AND c1cc(ccc1C=C)N 65.75 1.53e-16 14 356 117 195627

Table 3. Substructure Enrichment help

View Full Report

# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)N(C)C AND C(=CNC)(C(=N)C)CC AND c1(ccccc1)CC=C 215.88 4.41e-15 11 356 28 195627
2 c1cc(ccc1C=C)N AND c1c(cccc1N)O AND c1(ccccc1)N(C)C 111.93 4.35e-12 11 356 54 195627
3 C1(=CCC=CC1C)O AND c1cc(ccc1C=C)N AND c1(ccccc1)N(C)C 107.94 6.46e-12 11 356 56 195627
4 C(=CC)N(CC)C AND c1(ccccc1)C=N AND c1(ccccc1)N(C)C 90.21 4.59e-11 11 356 67 195627
5 c1(ccccc1)O AND c1cc(ccc1C=C)N AND c1(ccccc1)N(C)C 84.04 1.03e-13 13 356 85 195627