Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 1595 6293

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C1(C(C1)CCN)CNC 17.08 3.72e-11 26 1596 6 6293
2 C(CC(CN)C)CC(N)C 13.4 1.37e-13 34 1596 10 6293
3 C(C(=O)NC)C1C(C1)C 12.22 8.62e-12 31 1596 10 6293
4 C(CNC)C1CC1 9.7 7.40e-11 32 1596 13 6293
5 C(CC(CN)C)C(CN)C 9.01 2.11e-10 32 1596 14 6293

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 n1c(ccnc1)N AND c1(ccccc1)OCO 197.14 2.61e-29 50 1596 1 6293
2 c1ncccn1 AND c1(cc(ccc1N)O)C 169.54 2.22e-24 43 1596 1 6293
3 C1(=CCN=CN1)NCC AND C1(=CCC=CC1O)O 161.66 5.68e-23 41 1596 1 6293
4 C(=C)N AND n1c(ccnc1C)NC 126.17 1.18e-16 32 1596 1 6293
5 c1c(cccc1C)O AND C1(=NCN=CC1C)NC 114.34 1.50e-14 29 1596 1 6293

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1ncccn1 AND c1(ccccc1)OCO AND n1c(ccnc1)N 197.14 4.59e-26 50 1596 1 6293
2 c1ncccn1 AND C1(=CC(C=CC1)O)C=C AND C(CC)N 169.54 3.91e-21 43 1596 1 6293
3 c1ncccn1 AND c1(ccccc1)OCO AND C1(=CCN=CN1)NCC 161.66 9.98e-20 41 1596 1 6293
4 C(=C)C=C AND n1c(nccc1N)C AND c1(ccccc1)C 134.06 4.11e-15 34 1596 0 6293
5 C(=C)N AND n1c(nccc1N)C AND C1(=CCN=CN1)NC 126.17 2.08e-13 32 1596 1 6293