Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 222 7609

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(=N)(CNCCC)CSC 37.7 9.09e-11 11 222 10 7609
2 C(C(=NC)C=C)NCCC 30.84 7.78e-17 18 222 20 7609
3 C(=CC)(C(=N)CNC)SC 29.37 2.49e-22 24 222 28 7609
4 C(=NC)(CNCC)CS 28.86 1.49e-14 16 222 19 7609
5 C(=NC)(CNCC)C=C 24.84 1.21e-25 29 222 40 7609

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)C(=N)C AND C1CNCCN1 126.81 2.45e-45 37 222 10 7609
2 c1(ncccn1)NCC AND c1cc(ccc1C=N)F 111.39 3.38e-13 13 222 4 7609
3 C(=CC)CC AND n1c(c(cnc1O)N)N 109.67 5.40e-17 16 222 5 7609
4 c1(ncccn1)N(C)C AND c1cc(ccc1Cl)C 102.82 1.04e-11 12 222 4 7609
5 c1(ncccn1)NCC AND C1(=CC(C=C(C1)C)F)F 102.82 2.56e-19 18 222 6 7609

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)CC=O AND c1(ncccn1)NCC AND c1(ccccc1)CN 582.67 2.52e-19 17 222 1 7609
2 c1(ccccc1)CC=O AND c1(ncccn1)N(C)C AND c1(ccccc1)CN 582.67 2.52e-19 17 222 1 7609
3 c1(ccccc1)C(=N)C AND C1CNCCN1 AND F 514.12 3.65e-16 15 222 1 7609
4 c1(ccccc1)CC=O AND c1cc(ccc1CN)F AND c1(ncccn1)N 479.84 6.90e-15 14 222 0 7609
5 c1(ccccc1)CC=O AND c1(ncccn1)NCC AND c1cc(ccc1CN)F 342.74 1.33e-08 10 222 0 7609