Substructure Enrichment Report

Mapping Details for your submission help

# Active Inactive
Your Submission 345 56358

Table 1. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(C(=CNC)C)C=CC=C 13.13 4.06e-07 11 347 136 56358
2 C(=CC)(CC=CN)C(=O)O 10.57 4.20e-06 11 347 169 56358
3 C(=CC)(C(=O)OC)C(C)C 9.55 1.23e-05 11 347 187 56358
4 C(=CNN)(CC=CC)C 9.19 4.74e-06 12 347 212 56358
5 C(C(=CN)C)(C=CC)CC 9.06 2.15e-05 11 347 197 56358

Table 2. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 c1(ccccc1)NC=C AND C(=N)(C=C)CC 25.37 8.83e-06 10 347 64 56358
2 C(=CNC)C=N AND C(=CC=C)CCC 24.24 1.38e-05 10 347 67 56358
3 C(C(=CN)C)C=CC AND C(=CNC)(C(=N)C)C 23.88 1.60e-05 10 347 68 56358
4 c1(ccccc1)NC AND C(C=CC=C)C(=CN)C 21.94 3.71e-05 10 347 74 56358
5 C(=CCC)C=C AND C(=CNC)(C(=N)C)C 21.94 3.71e-05 10 347 74 56358

Table 3. Substructure Enrichment help

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# Substructure Odds Ratio p-value kA Active kB InActive
1 C(C(=CN)C)C=CC AND C(=CNC)(C(=N)C)C AND c1(ccccc1)NC=C 40.6 0.00012 10 347 40 56358
2 c1(ccccc1)NC=C AND C(=N)(C=C)CC AND C(=CNC)(C=N)C 36.91 0.00031 10 347 44 56358
3 C(=N)(C(=C)C)C AND C(=N)(C=CC)CC AND c1(ccccc1)NC 35.3 0.00048 10 347 46 56358
4 c1(ccccc1)NC AND C(C=CC=C)C(=CN)C AND O(CC)C 33.83 0.00073 10 347 48 56358
5 C(=CC)C(=N)C AND c1(ccccc1)NC=C AND C(=CC)C=C 33.83 0.00073 10 347 48 56358