Target/Pathway Enrichment Report

Mapping Details for your submissionhelp

# Active Inactive
Your Submission 952 235083
Mapped to Target 953 235083
Mapped to Reactome 953 235083
Mapped to GO 953 235083

Table 1. Target/MultiTarget Enrichment help

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# TARGET/MULTI-TARGET Odds Ratio p-value kA size
Active
kB size
InActive
1 gene: DAGLB inhibitor (gi:218931251, assay: 504411)
17.78 1.29e-08 11 953 131 201797
2 gene: DAGLB inhibitor (gi:218931251, 2 assays integrated)
17.64 1.40e-08 11 953 132 201797
3 gene: MMP14 activator (gi:4826834, assay: 651647)
16.63 2.68e-08 11 953 140 201797
4 gene: MAPK1 inhibitor (gi:66932916, assay: 1454)
16.4 4.42e-26 33 953 426 201797
5 gene: AMA1 inhibitor (gi:23496270, assay: 720542)
12.45 3.50e-18 27 953 459 201797

Table 2. Pathway Enrichment help

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# GO Term Odds Ratio p-value kA size
Active
kB size
InActive
1 (inhibitor) Effects of PIP2 hydrolysis 15.63 2.10e-08 11 666 139 131609
2 (activator) Activation of Matrix Metalloproteinases 15.52 2.28e-08 11 666 140 131609
3 (activator) Collagen degradation 15.52 2.28e-08 11 666 140 131609
4 (inhibitor) Recycling pathway of L1 10.84 1.20e-25 40 666 729 131609
5 (inhibitor) Negative regulation of FGFR3 signaling 9.21 4.48e-23 40 666 858 131609

Table 3. GO term Enrichment help

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# GO Term Odds Ratio p-value kA size
Active
kB size
InActive
1 (activator) collagen catabolic process 16.27 3.71e-08 11 718 140 148681
2 (activator) response to mechanical stimulus 16.04 4.33e-08 11 718 142 148681
3 (inhibitor) ERK1 and ERK2 cascade 11.36 6.19e-26 40 718 729 148681
4 (inhibitor) sensory perception of pain 10.81 3.79e-25 40 718 766 148681
5 (inhibitor) phosphatase binding 10.6 7.70e-25 40 718 781 148681