Target/Pathway Enrichment Report

Mapping Details for your submissionhelp

# Active Inactive
Your Submission 2428 300942
Mapped to Target 2434 300942
Mapped to Reactome 2434 300942
Mapped to GO 2434 300942

Table 1. Target/MultiTarget Enrichment help

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# TARGET/MULTI-TARGET Odds Ratio p-value kA size
Active
kB size
InActive
1 gi:74959757 interactor (assay: 1207598)
209.96 1.65e-16 10 2434 5 255532
2 gene: NR5A2 agonist (gi:4504343, assay: 602396)
134.04 1.00e-216 143 2434 112 255532
3 gi:9629429 agonist (assay: 651615)
109.8 3.65e-96 319 2434 305 255532
4 gi:9629429 agonist (assay: 624379)
102.41 3.65e-96 239 2434 245 255532
5 gene: S1PR2 antagonist (gi:134244587, 2 assays integrated)
92.12 1.51e-120 86 2434 98 255532

Table 2. Pathway Enrichment help

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# GO Term Odds Ratio p-value kA size
Active
kB size
InActive
1 (activator) Cellular response to heat stress 61.51 1.83e-33 27 2366 31 167102
2 (activator) Regulation of HSF1-mediated heat shock response 61.51 1.83e-33 27 2366 31 167102
3 (activator) Regulation of mRNA stability by proteins that bind AU-rich elements 53.44 2.01e-33 28 2366 37 167102
4 (inhibitor) Diseases of Immune System 29.18 1.54e-110 112 2366 271 167102
5 (inhibitor) Diseases associated with the TLR signaling cascade 29.18 1.54e-110 112 2366 271 167102

Table 3. GO term Enrichment help

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# GO Term Odds Ratio p-value kA size
Active
kB size
InActive
1 (inhibitor) digestive tract development 41.59 8.47e-11 10 2386 19 188567
2 (activator) response to retinoic acid 39.14 2.78e-172 157 2386 317 188567
3 (inhibitor) camera-type eye development 38.71 3.98e-96 705 2386 1439 188567
4 (agonist) positive regulation of inflammatory response 32.33 4.39e-55 54 2386 132 188567
5 (antagonist) digestion 32.16 8.37e-144 140 2386 344 188567