Target/Pathway Enrichment Report

Mapping Details for your submissionhelp

# Active Inactive
Your Submission 900 131877
Mapped to Target 904 131877
Mapped to Reactome 904 131877
Mapped to GO 904 131877

Table 1. Target/MultiTarget Enrichment help

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# TARGET/MULTI-TARGET Odds Ratio p-value kA size
Active
kB size
InActive
1 gi:486173 interactor (assay: 2271)
25.63 4.65e-16 17 904 87 118615
2 gene: VDR inhibitor (gi:63054845, assay: 602199)
24.14 2.75e-43 46 904 250 118615
3 gi:486173 interactor (assay: 2745)
22.44 1.90e-11 13 904 76 118615
4 gene: VDR inhibitor (gi:63054845, assay: 602200)
19.03 1.02e-15 19 904 131 118615
5 gene: S1PR4 antagonist (gi:15929025, assay: 1524)
18.98 3.93e-19 23 904 159 118615

Table 2. Pathway Enrichment help

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# GO Term Odds Ratio p-value kA size
Active
kB size
InActive
1 (activator) Cellular response to heat stress 32.78 1.21e-10 10 730 37 88557
2 (activator) Regulation of HSF1-mediated heat shock response 32.78 1.21e-10 10 730 37 88557
3 (activator) Regulation of mRNA stability by proteins that bind AU-rich elements 29.58 3.22e-10 10 730 41 88557
4 (interactor) Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity 12.76 4.32e-08 12 730 114 88557
5 (interactor) Trafficking of AMPA receptors 12.76 4.32e-08 12 730 114 88557

Table 3. GO term Enrichment help

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# GO Term Odds Ratio p-value kA size
Active
kB size
InActive
1 (inhibitor) positive regulation of release of cytochrome c from mitochondria 13.37 2.02e-06 10 773 94 97164
2 (interactor) endocytic vesicle membrane 13.23 8.04e-08 12 773 114 97164
3 (inhibitor) positive regulation of cell cycle 12.56 3.70e-06 10 773 100 97164
4 (inhibitor) endomembrane system 12.34 8.88e-07 11 773 112 97164
5 (inhibitor) cell morphogenesis 11.61 1.36e-64 96 773 1039 97164